CALL FOR PAPERS Pathophysiology of Hypertension Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in -amyloid generation and Alzheimer’s disease
نویسندگان
چکیده
Anna Csiszar, Zsuzsanna Tucsek, Peter Toth, Danuta Sosnowska, Tripti Gautam, Akos Koller, Ferenc Deak, William E. Sonntag, and Zoltan Ungvari Reynolds Oklahoma Center on Aging, Donald W. Reynolds Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma; Department of Pathophysiology and Gerontology, Medical School and Szentágothai Research Centre, University of Pecs, Pecs, Hungary; and The Peggy and Charles Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
منابع مشابه
Thymoquinone recovers learning function in a rat model of Alzheimer’s disease
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Aging, as a major risk factor of memory deficiency, affects neural signaling pathways in hippocampus. In particular, age-dependent androgens deficiency causes cognitive impairments. Several enzymes like protein kinase C (PKC) are involved in memory deficiency. Indeed, PKC regulatory process mediates α-secretase activation to cleave APP in β-amyloid cascade and tau proteins phosphorylation mecha...
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